Simple strategies to reduce the pain and distress of childhood vaccination Vaccine injections are the most common cause of iatrogenic pain in childhood and may contribute to vaccine hesitancy across the lifespan. Although there are many simple, evidence-based strategies available to reduce this, most are not routinely used. Interventions to reduce vaccination pain in children include procedural, physical, process and psychological strategies. For example, for children of all ages, when more than one vaccine injection is scheduled for the same visit...